{
  "_id": "6acbaf53fe5cc25786e924f5",
  "Package": "hsrecombi",
  "Type": "Package",
  "Title": "Estimation of Recombination Rate and Maternal LD in Half-Sibs",
  "Version": "1.1.1",
  "Date": "2026-04-12",
  "Authors@R": "c(person(\"Dörte\",\"Wittenburg\", role = c(\"aut\", \"cre\"), \nemail = \"wittenburg@fbn-dummerstorf.de\"))",
  "Description": "Paternal recombination rate and maternal linkage\ndisequilibrium (LD) are estimated for pairs of biallelic\nmarkers such as single nucleotide polymorphisms (SNPs) from\nprogeny genotypes and sire haplotypes. The implementation\nrelies on paternal half-sib families. If maternal half-sib\nfamilies are used, the roles of sire/dam are swapped. Multiple\nfamilies can be considered. For parameter estimation, at least\none sire has to be double heterozygous at the investigated\npairs of SNPs. Based on recombination rates, genetic distances\nbetween markers can be estimated. Markers with unusually large\nrecombination rate to markers in close proximity (i.e.\nputatively misplaced markers) shall be discarded in this\nderivation. *A pipeline is available at GitHub*\n<https://github.com/wittenburg/hsrecombi> Hampel, Teuscher,\nGomez-Raya, Doschoris, Wittenburg (2018) \"Estimation of\nrecombination rate and maternal linkage disequilibrium in\nhalf-sibs\" <doi:10.3389/fgene.2018.00186>. Gomez-Raya (2012)\n\"Maximum likelihood estimation of linkage disequilibrium in\nhalf-sib families\" <doi:10.1534/genetics.111.137521>.",
  "License": "GPL (>= 2)",
  "Encoding": "UTF-8",
  "LazyData": "true",
  "RoxygenNote": "7.3.3",
  "Language": "en-GB",
  "NeedsCompilation": "yes",
  "Packaged": {
    "Date": "2026-10-11 15:31:35 UTC",
    "User": "root"
  },
  "Author": "Dörte Wittenburg [aut, cre]",
  "Maintainer": "Dörte Wittenburg <wittenburg@fbn-dummerstorf.de>",
  "Config/pak/sysreqs": "libxml2-dev libssl-dev",
  "Repository": "https://wittenburg.r-universe.dev",
  "Date/Publication": "2026-04-12 17:55:08 UTC",
  "RemoteUrl": "https://github.com/cran/hsrecombi",
  "RemoteRef": "HEAD",
  "RemoteSha": "b929bb4e8670df62aa281ab10ae87263b0db3045",
  "_user": "wittenburg",
  "_type": "src",
  "_file": "hsrecombi_1.1.1.tar.gz",
  "_fileid": "https://r2.ropensci.org/1be13d14cb0dc46130df5dc9929b456defa6adfc1feabdc33817e8f4a2528bfe",
  "_filesize": 196145,
  "_sha256": "1be13d14cb0dc46130df5dc9929b456defa6adfc1feabdc33817e8f4a2528bfe",
  "_expires": "2027-01-19T15:46:26.000Z",
  "_created": "2026-10-11T15:31:35.000Z",
  "_published": "2026-10-11T15:46:27.826Z",
  "_buildurl": "https://github.com/r-universe/wittenburg/actions/runs/38151446447",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_jobs": [
    {
      "job": 114506213657,
      "time": 112,
      "config": "linux-devel-arm64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "11707485206"
    },
    {
      "job": 114506213708,
      "time": 130,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "11707210951"
    },
    {
      "job": 114506213665,
      "time": 93,
      "config": "linux-release-arm64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11706229040"
    },
    {
      "job": 114506213746,
      "time": 134,
      "config": "linux-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11706699517"
    },
    {
      "job": 114506213702,
      "time": 182,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "11706836941"
    },
    {
      "job": 114506213790,
      "time": 315,
      "config": "macos-oldrel-x86_64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "11707041673"
    },
    {
      "job": 114506213706,
      "time": 180,
      "config": "macos-release-arm64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11706906833"
    },
    {
      "job": 114506213735,
      "time": 713,
      "config": "macos-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": ""
    },
    {
      "job": 114505647539,
      "time": 157,
      "config": "source",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11707305418"
    },
    {
      "job": 114506213651,
      "time": 94,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "11706174132"
    },
    {
      "job": 114506213721,
      "time": 359,
      "config": "windows-devel-arm64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "11707520441"
    },
    {
      "job": 114506213749,
      "time": 116,
      "config": "windows-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "11706896413"
    },
    {
      "job": 114506213741,
      "time": 107,
      "config": "windows-oldrel-x86_64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "11707290586"
    },
    {
      "job": 114506213699,
      "time": 356,
      "config": "windows-release-arm64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11706762367"
    },
    {
      "job": 114506213827,
      "time": 114,
      "config": "windows-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11705979395"
    }
  ],
  "_upstream": "https://github.com/cran/hsrecombi",
  "_commit": {
    "id": "b929bb4e8670df62aa281ab10ae87263b0db3045",
    "author": "Dörte Wittenburg <wittenburg@fbn-dummerstorf.de>",
    "committer": "cran-robot <csardi.gabor+cran@gmail.com>",
    "message": "version 1.1.1\n",
    "time": 1776016508
  },
  "_maintainer": {
    "name": "Dörte Wittenburg",
    "email": "wittenburg@fbn-dummerstorf.de",
    "login": "wittenburg",
    "description": "",
    "uuid": 34709155
  },
  "_distro": "resolute",
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 3.5.0",
      "role": "Depends"
    },
    {
      "package": "Rcpp",
      "role": "LinkingTo"
    },
    {
      "package": "Rcpp",
      "version": ">= 1.0.3",
      "role": "Imports"
    },
    {
      "package": "hsphase",
      "role": "Imports"
    },
    {
      "package": "dplyr",
      "role": "Imports"
    },
    {
      "package": "data.table",
      "role": "Imports"
    },
    {
      "package": "rlist",
      "role": "Imports"
    },
    {
      "package": "quadprog",
      "role": "Imports"
    },
    {
      "package": "curl",
      "role": "Imports"
    },
    {
      "package": "Matrix",
      "role": "Imports"
    },
    {
      "package": "magrittr",
      "role": "Imports"
    }
  ],
  "_owner": "cran",
  "_selfowned": true,
  "_usedby": 0,
  "_updates": [
    {
      "week": "2026-13",
      "n": 1
    },
    {
      "week": "2026-15",
      "n": 1
    }
  ],
  "_tags": [
    {
      "name": "1.1.0",
      "date": "2026-03-27"
    },
    {
      "name": "1.1.1",
      "date": "2026-04-12"
    }
  ],
  "_stars": 0,
  "_contributors": [
    {
      "user": "wittenburg",
      "count": 12,
      "uuid": 34709155
    }
  ],
  "_userbio": {
    "uuid": 34709155,
    "type": "user",
    "name": "wittenburg",
    "followers": 4
  },
  "_downloads": {
    "count": 463,
    "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/hsrecombi"
  },
  "_searchresults": 10,
  "_topics": [
    "cpp"
  ],
  "_rbuild": "4.6.1",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/hsrecombi.html",
    "extra/manual.pdf",
    "extra/NEWS.html",
    "extra/NEWS.txt"
  ],
  "_realowner": "wittenburg",
  "_cranurl": false,
  "_releases": [
    {
      "version": "0.1.3",
      "date": "2020-03-04"
    },
    {
      "version": "0.3.0",
      "date": "2020-05-28"
    },
    {
      "version": "0.3.1",
      "date": "2020-08-27"
    },
    {
      "version": "0.3.2",
      "date": "2020-10-14"
    },
    {
      "version": "0.3.4",
      "date": "2021-03-23"
    },
    {
      "version": "0.4.1",
      "date": "2022-03-24"
    },
    {
      "version": "0.4.2",
      "date": "2022-03-27"
    },
    {
      "version": "0.5.0",
      "date": "2022-11-29"
    },
    {
      "version": "0.5.1",
      "date": "2022-12-01"
    },
    {
      "version": "1.0.1",
      "date": "2023-06-07"
    },
    {
      "version": "1.1.0",
      "date": "2026-03-27"
    },
    {
      "version": "1.1.1",
      "date": "2026-04-12"
    }
  ],
  "_exports": [
    "bestmapfun",
    "checkCandidates",
    "editraw",
    "felsenstein",
    "geneticPosition",
    "haldane",
    "hsrecombi",
    "karlin",
    "kosambi",
    "LDHScpp",
    "makehap",
    "makehaplist",
    "makehappm",
    "rao",
    "rao.inv",
    "startvalue"
  ],
  "_datasets": [
    {
      "name": "daughterSire",
      "title": "targetregion: allocation of paternal half-sib families",
      "object": "targetregion",
      "class": [
        "integer"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "genotype.chr",
      "title": "targetregion: progeny genotypes",
      "object": "targetregion",
      "class": [
        "matrix",
        "array"
      ],
      "fields": [],
      "rows": 265,
      "table": true,
      "tojson": true
    },
    {
      "name": "hapSire",
      "title": "targetregion: sire haplotypes",
      "object": "targetregion",
      "class": [
        "matrix",
        "array"
      ],
      "fields": [],
      "rows": 10,
      "table": true,
      "tojson": true
    },
    {
      "name": "map.chr",
      "title": "targetregion: physical map",
      "object": "targetregion",
      "class": [
        "data.frame"
      ],
      "fields": [
        "SNP",
        "Chr",
        "locus_bp",
        "locus_Mb",
        "markername",
        "SNP_btau42"
      ],
      "rows": 200,
      "table": true,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "bestmapfun",
      "title": "Best fitting genetic-map function",
      "topics": [
        "bestmapfun"
      ]
    },
    {
      "page": "checkCandidates",
      "title": "Candidates for misplacement",
      "topics": [
        "checkCandidates"
      ]
    },
    {
      "page": "countNumbers",
      "title": "Count genotype combinations at 2 SNPs",
      "topics": [
        "countNumbers"
      ]
    },
    {
      "page": "daughterSire",
      "title": "targetregion: allocation of paternal half-sib families",
      "topics": [
        "daughterSire"
      ]
    },
    {
      "page": "editraw",
      "title": "Editing results of hsrecombi",
      "topics": [
        "editraw"
      ]
    },
    {
      "page": "felsenstein",
      "title": "Felsenstein's genetic map function",
      "topics": [
        "felsenstein"
      ]
    },
    {
      "page": "geneticPosition",
      "title": "Estimation of genetic position",
      "topics": [
        "geneticPosition"
      ]
    },
    {
      "page": "genotype.chr",
      "title": "targetregion: progeny genotypes",
      "topics": [
        "genotype.chr"
      ]
    },
    {
      "page": "haldane",
      "title": "Haldane's genetic map function",
      "topics": [
        "haldane"
      ]
    },
    {
      "page": "hapSire",
      "title": "targetregion: sire haplotypes",
      "topics": [
        "hapSire"
      ]
    },
    {
      "page": "hsrecombi",
      "title": "Estimation of recombination rate and maternal LD",
      "topics": [
        "hsrecombi"
      ]
    },
    {
      "page": "karlin",
      "title": "Liberman and Karlin's genetic map function",
      "topics": [
        "karlin"
      ]
    },
    {
      "page": "kosambi",
      "title": "Kosambi's genetic map function",
      "topics": [
        "kosambi"
      ]
    },
    {
      "page": "LDHScpp",
      "title": "Expectation Maximisation (EM) algorithm",
      "topics": [
        "LDHScpp"
      ]
    },
    {
      "page": "loglikfun",
      "title": "Calculate log-likelihood function",
      "topics": [
        "loglikfun"
      ]
    },
    {
      "page": "makehap",
      "title": "Make list of imputed sire haplotypes",
      "topics": [
        "makehap"
      ]
    },
    {
      "page": "makehaplist",
      "title": "Make list of sire haplotypes",
      "topics": [
        "makehaplist"
      ]
    },
    {
      "page": "makehappm",
      "title": "Make list of imputed haplotypes and estimate recombination rate",
      "topics": [
        "makehappm"
      ]
    },
    {
      "page": "map.chr",
      "title": "targetregion: physical map",
      "topics": [
        "map.chr"
      ]
    },
    {
      "page": "rao",
      "title": "System of genetic-map functions",
      "topics": [
        "rao"
      ]
    },
    {
      "page": "rao-inverse",
      "title": "Approximation to inverse of Rao's system of map functions",
      "topics": [
        "rao inverse",
        "rao.inv"
      ]
    },
    {
      "page": "startvalue",
      "title": "Start value for maternal allele and haplotype frequencies",
      "topics": [
        "startvalue"
      ]
    },
    {
      "page": "targetregion",
      "title": "Description of the targetregion data set",
      "topics": [
        "targetregion"
      ]
    }
  ],
  "_rundeps": [
    "cli",
    "curl",
    "data.table",
    "dplyr",
    "gdata",
    "generics",
    "glue",
    "gtools",
    "hsphase",
    "jsonlite",
    "lattice",
    "lifecycle",
    "magrittr",
    "Matrix",
    "pillar",
    "pkgconfig",
    "quadprog",
    "R6",
    "Rcpp",
    "RcppArmadillo",
    "rlang",
    "rlist",
    "snow",
    "snowfall",
    "tibble",
    "tidyselect",
    "utf8",
    "vctrs",
    "withr",
    "XML",
    "yaml"
  ],
  "_sysdeps": [
    {
      "shlib": "libstdc++",
      "package": "libstdc++6",
      "source": "gcc",
      "version": "16-20260322-1ubuntu1",
      "name": "c++",
      "homepage": "http://gcc.gnu.org/",
      "description": "GNU Standard C++ Library v3"
    }
  ],
  "_score": 1.3010299956639813,
  "_indexed": true,
  "_nocasepkg": "hsrecombi",
  "_universes": [
    "wittenburg"
  ],
  "_binaries": [
    {
      "r": "4.6.1",
      "os": "mac",
      "version": "1.1.1",
      "date": "2026-09-10T08:41:07.000Z",
      "arch": "x86_64",
      "commit": "b929bb4e8670df62aa281ab10ae87263b0db3045",
      "fileid": "https://r2.ropensci.org/e5aa2373475045fcb5dd12e3c2ac73ad58a65d2d9a20bc15e658722a6b90a255",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wittenburg/actions/runs/34455813882"
    },
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.1.1",
      "date": "2026-10-11T15:33:18.000Z",
      "distro": "resolute",
      "arch": "aarch64",
      "commit": "b929bb4e8670df62aa281ab10ae87263b0db3045",
      "fileid": "https://r2.ropensci.org/cc56dda533ea8148d07ea956d8ec195fbd56790f21d1ba7e8b17e3d1d8de36df",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wittenburg/actions/runs/38151446447"
    },
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.1.1",
      "date": "2026-10-11T15:33:31.000Z",
      "distro": "resolute",
      "arch": "x86_64",
      "commit": "b929bb4e8670df62aa281ab10ae87263b0db3045",
      "fileid": "https://r2.ropensci.org/1c66f28b544f321ac404336db50540d1e40441da55dd3de82172b5fc7c1236a4",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wittenburg/actions/runs/38151446447"
    },
    {
      "r": "4.6.1",
      "os": "linux",
      "version": "1.1.1",
      "date": "2026-10-11T15:33:09.000Z",
      "distro": "resolute",
      "arch": "aarch64",
      "commit": "b929bb4e8670df62aa281ab10ae87263b0db3045",
      "fileid": "https://r2.ropensci.org/798680e78b397f91dad16a9679fa9eb96b1ac1f322e63cff039f836987f983fc",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wittenburg/actions/runs/38151446447"
    },
    {
      "r": "4.6.1",
      "os": "linux",
      "version": "1.1.1",
      "date": "2026-10-11T15:33:29.000Z",
      "distro": "resolute",
      "arch": "x86_64",
      "commit": "b929bb4e8670df62aa281ab10ae87263b0db3045",
      "fileid": "https://r2.ropensci.org/5985545593dcb820100333cd0e73a774609c8661430b5b23c4a488c9ad7af90b",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wittenburg/actions/runs/38151446447"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.1.1",
      "date": "2026-10-11T15:37:09.000Z",
      "arch": "aarch64",
      "commit": "b929bb4e8670df62aa281ab10ae87263b0db3045",
      "fileid": "https://r2.ropensci.org/671bde5d787a4284af595fbfa3517948319c6afa080d12a748bbb0eb6d3ef17a",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wittenburg/actions/runs/38151446447"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.1.1",
      "date": "2026-10-11T15:37:06.000Z",
      "arch": "x86_64",
      "commit": "b929bb4e8670df62aa281ab10ae87263b0db3045",
      "fileid": "https://r2.ropensci.org/1f5fb2f262f56db1c4f4e0301daf1d9482d5f1e653f55827f85b06befde65797",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wittenburg/actions/runs/38151446447"
    },
    {
      "r": "4.6.1",
      "os": "mac",
      "version": "1.1.1",
      "date": "2026-10-11T15:36:41.000Z",
      "arch": "aarch64",
      "commit": "b929bb4e8670df62aa281ab10ae87263b0db3045",
      "fileid": "https://r2.ropensci.org/100c9eb59d02452ae9fed51cba028f0f9d74465f68f3374c79aca4796401fb51",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wittenburg/actions/runs/38151446447"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "1.1.1",
      "date": "2026-10-11T15:33:25.000Z",
      "arch": "emscripten",
      "commit": "b929bb4e8670df62aa281ab10ae87263b0db3045",
      "fileid": "https://r2.ropensci.org/888a037337455fd101e00d9c194fa0ea42c6fb66fceb18a684bbe06804d6e63b",
      "status": "success",
      "buildurl": "https://github.com/r-universe/wittenburg/actions/runs/38151446447"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.1.1",
      "date": "2026-10-11T15:36:29.000Z",
      "arch": "aarch64",
      "commit": "b929bb4e8670df62aa281ab10ae87263b0db3045",
      "fileid": "https://r2.ropensci.org/2e993de12ba2aeac5b617b8071a0fed6905b141c964cc96c2f9cd3738a2af932",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wittenburg/actions/runs/38151446447"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.1.1",
      "date": "2026-10-11T15:32:45.000Z",
      "arch": "x86_64",
      "commit": "b929bb4e8670df62aa281ab10ae87263b0db3045",
      "fileid": "https://r2.ropensci.org/a44398d20458067c0f891111d8426101c9b805880baa905455a0fdb26ddda1a8",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wittenburg/actions/runs/38151446447"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "1.1.1",
      "date": "2026-10-11T15:32:42.000Z",
      "arch": "x86_64",
      "commit": "b929bb4e8670df62aa281ab10ae87263b0db3045",
      "fileid": "https://r2.ropensci.org/083d247a612807a567b5eceea79e7e42cc8815a93b9abeaca3fe74d98cf5f400",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wittenburg/actions/runs/38151446447"
    },
    {
      "r": "4.6.1",
      "os": "win",
      "version": "1.1.1",
      "date": "2026-10-11T15:36:43.000Z",
      "arch": "aarch64",
      "commit": "b929bb4e8670df62aa281ab10ae87263b0db3045",
      "fileid": "https://r2.ropensci.org/4551a0826fd58a64adf2207674f1db87f1a478921e5e299b679d0ec3f5551171",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wittenburg/actions/runs/38151446447"
    },
    {
      "r": "4.6.1",
      "os": "win",
      "version": "1.1.1",
      "date": "2026-10-11T15:32:45.000Z",
      "arch": "x86_64",
      "commit": "b929bb4e8670df62aa281ab10ae87263b0db3045",
      "fileid": "https://r2.ropensci.org/0f56edfb78b413de4aa48ef9ac5cda3742fd2d9ba0a62ffeb290437676f1b32c",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wittenburg/actions/runs/38151446447"
    }
  ]
}