{ "_id": "6a10308eacfb0bcc41c95827", "Package": "hsrecombi", "Type": "Package", "Title": "Estimation of Recombination Rate and Maternal LD in Half-Sibs", "Version": "1.1.1", "Date": "2026-04-12", "Authors@R": "c(person(\"Dörte\",\"Wittenburg\", role = c(\"aut\", \"cre\"), \nemail = \"wittenburg@fbn-dummerstorf.de\"))", "Description": "Paternal recombination rate and maternal linkage\ndisequilibrium (LD) are estimated for pairs of biallelic\nmarkers such as single nucleotide polymorphisms (SNPs) from\nprogeny genotypes and sire haplotypes. The implementation\nrelies on paternal half-sib families. If maternal half-sib\nfamilies are used, the roles of sire/dam are swapped. Multiple\nfamilies can be considered. For parameter estimation, at least\none sire has to be double heterozygous at the investigated\npairs of SNPs. Based on recombination rates, genetic distances\nbetween markers can be estimated. Markers with unusually large\nrecombination rate to markers in close proximity (i.e.\nputatively misplaced markers) shall be discarded in this\nderivation. *A pipeline is available at GitHub*\n Hampel, Teuscher,\nGomez-Raya, Doschoris, Wittenburg (2018) \"Estimation of\nrecombination rate and maternal linkage disequilibrium in\nhalf-sibs\" . Gomez-Raya (2012)\n\"Maximum likelihood estimation of linkage disequilibrium in\nhalf-sib families\" .", "License": "GPL (>= 2)", "Encoding": "UTF-8", "LazyData": "true", "RoxygenNote": "7.3.3", "Language": "en-GB", "NeedsCompilation": "yes", "Packaged": { "Date": "2026-05-12 09:28:38 UTC", "User": "root" }, "Author": "Dörte Wittenburg [aut, cre]", "Maintainer": "Dörte Wittenburg ", "Config/pak/sysreqs": "libxml2-dev libssl-dev", "Repository": "https://wittenburg.r-universe.dev", "Date/Publication": "2026-04-12 17:55:08 UTC", "RemoteUrl": "https://github.com/cran/hsrecombi", "RemoteRef": "HEAD", "RemoteSha": "b929bb4e8670df62aa281ab10ae87263b0db3045", "MD5sum": "fa115183068ca3afd08e5855aa9e1f10", "_user": "wittenburg", "_type": "src", "_file": "hsrecombi_1.1.1.tar.gz", "_fileid": "6da6a9fc1182e0fd5dda3d36d4f942a9f29fca9e38ddaaf41d029e6f65aa896b", "_filesize": 197638, "_sha256": "6da6a9fc1182e0fd5dda3d36d4f942a9f29fca9e38ddaaf41d029e6f65aa896b", "_created": "2026-05-12T09:28:38.000Z", 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